Spinach Artichoke Grilled Cheese

Featured in: Weeknight Dinners

This dish features a creamy mix of sautéed spinach, chopped artichoke hearts, and a blend of mozzarella, cream, and Parmesan cheeses. The mixture is spread onto sourdough slices, buttered, and grilled until the bread is golden and the filling melts into a rich, savory delight. Ideal for a quick lunch or cozy dinner, it offers a satisfying vegetarian option that combines fresh vegetables and rich dairy flavors with a crisp, buttery crust.

Updated on Sun, 11 Jan 2026 09:19:00 GMT
Golden-brown spinach artichoke grilled cheese, oozing with melted cheese, ready to be enjoyed. Save to Pinterest
Golden-brown spinach artichoke grilled cheese, oozing with melted cheese, ready to be enjoyed. | yummywithmia.com

I stumbled onto this sandwich completely by accident on a Tuesday afternoon when I had spinach going soft in the crisper drawer and a half-empty jar of artichokes staring at me from the pantry shelf. Instead of tossing together a sad desk lunch, I thought—why not make something that actually feels special? That first bite, when the warm cheese hit my tongue and the roasted earthiness of the artichoke came through, I realized I'd just accidentally reinvented an old favorite into something I'd actually crave.

My neighbor smelled it cooking through our shared wall and actually knocked to ask what I was making. We ended up splitting one of these with tomato soup on her kitchen counter, and she asked for the recipe before we even finished eating. Sometimes the best part of cooking isn't the food—it's that moment when someone else gets it.

Ingredients

  • Shredded mozzarella cheese (1 cup): This is your workhorse—it melts fast and creates that stretch, but cream cheese is what stops it from being greasy.
  • Cream cheese, softened (1/2 cup): The secret binder that makes the filling creamy instead of just a pile of melted cheese.
  • Grated Parmesan cheese (1/4 cup): Adds a salty, umami depth that elevates this from simple to sophisticated.
  • Unsalted butter, softened (2 tablespoons): Spread it on the bread before cooking—this is what gets you that proper golden-brown crust.
  • Fresh spinach, chopped (1 cup): Sauté it first to release moisture; frozen will work too, just squeeze it dry.
  • Canned or jarred artichoke hearts, drained and chopped (1/2 cup): Drain them really well or your filling gets watery and the sandwich gets soggy.
  • Garlic clove, minced (1 small): Raw garlic here brings a sharp note—use less if you're sensitive, more if you love that punch.
  • Sourdough bread (4 slices): Thick-cut sourdough holds up to pressure and absorbs butter perfectly without falling apart.
  • Salt, pepper, and red pepper flakes: The salt brightens the spinach, pepper adds warmth, and red flakes give an optional kick.

Instructions

Wilt and drain the spinach:
Toss fresh spinach into a medium skillet with just a splash of water—you'll hear it hiss and collapse in about a minute. Pour it into a fine strainer and press gently with the back of a spoon to squeeze out every drop of moisture, or your sandwich will become a soggy mess.
Mix your filling:
In a bowl, combine the spinach, chopped artichokes, softened cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and a pinch of red pepper flakes if you like heat. Stir until it looks creamy and everything is evenly distributed—no pockets of unmixed cream cheese.
Assemble the sandwiches:
Lay two slices of sourdough on a clean surface and spread half the filling generously onto each slice. Top each with another slice of bread, pressing down gently so it sticks together.
Butter the outside:
Using a butter knife or your fingers, spread softened butter evenly across both the top and bottom of each sandwich. Don't skimp—this is what creates that golden, crispy exterior.
Cook low and slow:
Heat your skillet or griddle over medium heat and let it warm for a minute. Place the sandwiches in the pan and cook for 3 to 4 minutes without moving them, then gently press down with a spatula, flip, and cook the other side for another 3 to 4 minutes until both sides are deep golden brown and the cheese is completely melted inside. You'll smell when it's done.
Rest and serve:
Remove the sandwiches to a cutting board and let them sit for 30 seconds—this lets the cheese set just slightly so it doesn't ooze everywhere when you bite. Slice in half diagonally and serve immediately.
Save to Pinterest
| yummywithmia.com

There's something almost meditative about watching the butter foam on the skillet's surface and knowing that in the next few minutes, someone is going to bite into something warm and melted and made by your own hands. That's when cooking stops being a task and becomes a small act of care.

The Sourdough Makes All the Difference

Sourdough's tang and sturdy crumb stand up to the moisture and weight of a creamy filling where regular white bread would collapse. The slight sourness also plays beautifully against the richness of the cheese and cream, creating balance on your palate. If you can't find sourdough, ciabatta works too, but avoid anything soft or thin—you need structure here.

Why This Filling Works

The combination of cream cheese and mozzarella is the real magic. Mozzarella alone stretches and pulls, which looks nice but can be slippery; cream cheese binds everything together, holds the vegetables in place, and creates a spread that actually stays where you put it. The Parmesan adds funk and keeps the filling from feeling one-note. This isn't just melted cheese—it's engineered to stay put and taste complex.

Make It Your Own

Start with this base and build from there once you've nailed the technique. Some mornings I add crispy bacon or thin tomato slices; other times I'll swap in a handful of roasted red peppers or a layer of pesto. The filling is forgiving, and the process stays exactly the same.

  • A sprinkle of smoked paprika in the filling adds a subtle smokiness that nobody can quite identify but everyone loves.
  • Fresh basil stirred in at the end brings brightness, but add it just before assembling so it doesn't wilt completely.
  • Caramelized onions take this from quick lunch to something you'd order at a restaurant.
Close-up of a perfectly grilled spinach artichoke grilled cheese, served hot and delicious for lunch. Save to Pinterest
Close-up of a perfectly grilled spinach artichoke grilled cheese, served hot and delicious for lunch. | yummywithmia.com

This sandwich reminds me that sometimes the best meals come from looking at what you have on hand instead of what the recipe calls for. Make it, eat it warm, and share it if you can.

Common Recipe Questions

How do I prevent the bread from getting soggy?

Make sure to drain excess moisture from the sautéed spinach and artichokes before assembling. Buttering the outside of the bread also helps create a crisp barrier during grilling.

Can I use different bread types?

Yes, sourdough is recommended for its texture and flavor, but whole wheat or multigrain breads work well as nutritious variations.

What cheeses work best for the filling?

A combination of mozzarella, cream cheese, and Parmesan provides creaminess, meltability, and a savory depth that's perfect for this dish.

How long should I cook the sandwiches?

Cook each side for 3 to 4 minutes on medium heat until the bread is golden brown and the cheese filling is melted.

Can I add extra flavorings?

Fresh basil or a sprinkle of smoked paprika enhance the flavors, adding herbal or smoky notes that complement the filling.

Spinach Artichoke Grilled Cheese

Creamy spinach and artichoke filling with melted cheeses on sourdough bread, crisped to golden perfection.

Prep Time
15 minutes
Cooking Duration
10 minutes
Overall Time
25 minutes
Created by Mia

Recipe Type Weeknight Dinners

Skill Level Easy

Culinary Origin American

Total Output 2 Portion Size

Dietary Preferences Vegetarian-Friendly

What You'll Need

Dairy

01 1 cup shredded mozzarella cheese
02 1/2 cup cream cheese, softened
03 1/4 cup grated Parmesan cheese
04 2 tablespoons unsalted butter, softened

Vegetables

01 1 cup fresh spinach, chopped
02 1/2 cup canned or jarred artichoke hearts, drained and chopped
03 1 small garlic clove, minced

Bread

01 4 slices sourdough bread

Seasonings

01 1/4 teaspoon salt
02 1/8 teaspoon freshly ground black pepper
03 Pinch of red pepper flakes (optional)

Steps to Follow

Step 01

Wilt the spinach: Place spinach in a medium skillet over medium heat with a splash of water. Sauté until wilted, about 1 to 2 minutes. Drain any excess moisture.

Step 02

Prepare filling: In a mixing bowl, combine the sautéed spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, minced garlic, salt, black pepper, and red pepper flakes if using. Stir until evenly combined.

Step 03

Assemble sandwiches: Evenly spread the spinach and artichoke mixture onto two slices of sourdough bread. Top each with a remaining bread slice to form sandwiches.

Step 04

Butter bread exteriors: Lightly butter the outer sides of each sandwich to prepare for grilling.

Step 05

Grill sandwiches: Heat a nonstick skillet or griddle over medium heat. Cook sandwiches for 3 to 4 minutes per side, pressing gently, until the bread is golden brown and the cheese inside has melted.

Step 06

Serve: Remove sandwiches from heat, slice in half, and serve immediately.

Tools Required

  • Medium skillet
  • Mixing bowl
  • Spatula
  • Nonstick skillet or griddle
  • Knife

Allergy Warnings

Please review individual ingredients for potential allergens and reach out to a healthcare professional if unsure.
  • Contains milk (cheese, butter) and wheat (sourdough bread). May contain traces of soy or nuts depending on brands. Verify ingredient labels.

Nutritional Info (per serving)

These details are for reference only and shouldn't replace professional medical consultation.
  • Calories Count: 430
  • Fats: 24 grams
  • Carbohydrates: 39 grams
  • Proteins: 16 grams