One-Pot Cajun Chicken Alfredo

Featured in: Weeknight Dinners

This dish brings tender diced chicken together with orzo pasta simmered in a rich Cajun Alfredo sauce, blending spices like smoked paprika and red pepper flakes for a lively kick. The creamy sauce is created by stirring in heavy cream and Parmesan, giving a smooth texture that coats the pasta perfectly. Quick sautéed onions and garlic build a savory base, while fresh parsley adds a hint of brightness. Ready in just 30 minutes, it’s a flavorful and comforting one-pot meal great for busy evenings.

Updated on Sat, 22 Nov 2025 15:35:00 GMT
One-Pot Cajun Chicken Alfredo Orzo, a creamy, flavorful dish with tender chicken and al dente orzo pasta. Save to Pinterest
One-Pot Cajun Chicken Alfredo Orzo, a creamy, flavorful dish with tender chicken and al dente orzo pasta. | yummywithmia.com

A quick and creamy one-pot meal that blends tender chicken, al dente orzo, and a zesty Cajun Alfredo sauce. Perfect for busy weeknights, this dish delivers bold flavors and comforting richness in just 30 minutes.

This dish comes together quickly, making it ideal for busy evenings when you want something satisfying without the hassle.

Ingredients

  • Chicken: 1 lb (450 g) chicken breast, diced (substitute with shrimp or Andouille sausage if desired), salt and black pepper, to taste
  • Spice Blend: 1 tbsp Cajun seasoning (adjust for spice preference), 1 tsp smoked paprika (regular paprika can be used), 1/4 tsp red pepper flakes (optional for extra heat)
  • Base: 2 tbsp olive oil, 2 tbsp butter, 1 medium onion, chopped (yellow or sweet preferred), 3 cloves garlic, minced
  • Pasta: 1 cup (190 g) orzo pasta (substitute with other small pasta if needed)
  • Sauce: 2 cups (480 ml) low-sodium chicken broth, 1 cup (240 ml) heavy cream (or half and half for a lighter version), 1 cup (90 g) Parmesan cheese, freshly grated
  • Garnish: 1 tbsp fresh parsley, chopped

Instructions

Step 1:
Heat olive oil and butter in a large skillet over medium-high heat. Add diced chicken, season with salt and pepper, and sear for 3 to 4 minutes until golden brown. Remove chicken and set aside.
Step 2:
In the same skillet, add chopped onion and sauté for 2 to 3 minutes until translucent. Stir in minced garlic and cook for 1 minute until fragrant.
Step 3:
Add orzo pasta to the skillet, stirring to combine. Toast for 1 to 2 minutes until lightly golden.
Step 4:
Pour in chicken broth and sprinkle in Cajun seasoning, smoked paprika, and red pepper flakes. Stir well, bring to a boil, then reduce heat to low. Cover and simmer for 10 to 12 minutes, stirring occasionally, until orzo is al dente and most of the liquid is absorbed.
Step 5:
Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until the sauce is creamy and smooth.
Step 6:
Return the cooked chicken to the skillet and stir to combine. Heat through for 1 minute. Taste and adjust seasoning as needed.
Step 7:
Garnish with fresh parsley before serving.
Golden chicken pieces and creamy Cajun Alfredo sauce coat the orzo in this one-pot meal. Save to Pinterest
Golden chicken pieces and creamy Cajun Alfredo sauce coat the orzo in this one-pot meal. | yummywithmia.com

Serving this meal always brings warmth to our family dinners and invites wonderful conversations around the table.

Recipe Variations

Add bell peppers or spinach for extra vegetables and color.

Serving Suggestions

Serve with crusty bread or a green salad to complete the meal.

Pairings

Pairs well with a chilled Sauvignon Blanc or light lager.

Garnish this One-Pot Cajun Chicken Alfredo Orzo with fresh parsley; a comforting weeknight delight. Save to Pinterest
Garnish this One-Pot Cajun Chicken Alfredo Orzo with fresh parsley; a comforting weeknight delight. | yummywithmia.com

This recipe is a delightful blend of simplicity and flavor that makes weeknight dinners memorable.

Common Recipe Questions

Can I substitute the chicken with other proteins?

Yes, shrimp or Andouille sausage both work well and bring their own unique flavors. Adjust their cooking times accordingly for best results.

Is it possible to make this dish less rich?

Use half and half instead of heavy cream and slightly reduce the Parmesan cheese to lighten the sauce while maintaining creaminess.

What type of pasta can replace orzo?

Small pasta shapes similar to orzo, such as acini di pepe or small ditalini, can be used without altering the cooking process significantly.

How can I add more vegetables to this dish?

Ingredients like bell peppers or fresh spinach can be added during the sautéing steps to boost flavor and color.

What wine pairs well with this meal?

A chilled Sauvignon Blanc or a light lager complements the creamy and spicy elements nicely.

How do I ensure the orzo cooks perfectly?

Simmer the pasta in chicken broth with spices covered on low heat, stirring occasionally, until al dente and most liquid is absorbed.

One-Pot Cajun Chicken Alfredo

Tender chicken and orzo combine in a creamy Cajun sauce for a quick, comforting dinner.

Prep Time
10 minutes
Cooking Duration
20 minutes
Overall Time
30 minutes
Created by Mia

Recipe Type Weeknight Dinners

Skill Level Easy

Culinary Origin Cajun

Total Output 4 Portion Size

Dietary Preferences None specified

What You'll Need

Chicken

01 1 lb diced chicken breast
02 Salt, to taste
03 Black pepper, to taste

Spice Blend

01 1 tablespoon Cajun seasoning
02 1 teaspoon smoked paprika
03 1/4 teaspoon red pepper flakes (optional)

Base

01 2 tablespoons olive oil
02 2 tablespoons butter
03 1 medium onion, chopped
04 3 cloves garlic, minced

Pasta

01 1 cup orzo pasta

Sauce

01 2 cups low-sodium chicken broth
02 1 cup heavy cream
03 1 cup freshly grated Parmesan cheese

Garnish

01 1 tablespoon fresh parsley, chopped

Steps to Follow

Step 01

Sear Chicken: Heat olive oil and butter in a large skillet over medium-high heat. Season diced chicken with salt and black pepper; sear for 3 to 4 minutes until golden brown. Remove chicken and set aside.

Step 02

Sauté Aromatics: Add chopped onion to the same skillet and cook for 2 to 3 minutes until translucent. Stir in minced garlic and cook for 1 minute until fragrant.

Step 03

Toast Orzo: Add orzo pasta to the skillet and stir to combine. Toast pasta for 1 to 2 minutes until lightly golden.

Step 04

Simmer Orzo: Pour in chicken broth and add Cajun seasoning, smoked paprika, and red pepper flakes. Stir and bring to a boil, then reduce heat to low. Cover and simmer for 10 to 12 minutes, stirring occasionally, until orzo is al dente and liquid is mostly absorbed.

Step 05

Incorporate Sauce: Remove skillet from heat. Gradually stir in heavy cream and Parmesan cheese until sauce is creamy and smooth.

Step 06

Combine Chicken: Return cooked chicken to skillet and stir to combine. Warm through for 1 minute. Adjust seasoning if necessary.

Step 07

Garnish and Serve: Sprinkle chopped fresh parsley over the dish before serving.

Tools Required

  • Large skillet with lid
  • Wooden spoon or spatula
  • Chef’s knife
  • Cutting board
  • Measuring cups and spoons
  • Grater

Allergy Warnings

Please review individual ingredients for potential allergens and reach out to a healthcare professional if unsure.
  • Contains dairy and gluten.

Nutritional Info (per serving)

These details are for reference only and shouldn't replace professional medical consultation.
  • Calories Count: 560
  • Fats: 28 grams
  • Carbohydrates: 45 grams
  • Proteins: 35 grams